SETTING THE RIGHT
DOSE FOR EACH DOG
Start PEXION® at the initial recommended dose of 10 mg/kg:1
10 kg of body weight
= 100 mg tablet
20 kg of body weight
= 200 mg dose
(½ of 400 mg tablet)
40 kg of body weight
= 400 mg tablet
See below body weight chart for easy dosing customisation.
| Body weight (kg) | Number of tablets (administered twice daily) | |
|---|---|---|
| 100 mg tablet* | 400 mg tablet* | |
| 5.0 | 0.5 | |
| 5.1-10.1 | 1 | |
| 10.1-15.0 | 1.5 | |
| 15.1-20 | 0.5 | |
| 20.1-40.0 | 1 | |
| 40.1-60.0 | 1.5 | |
| Over 60.0 | 2 | |
If seizure control is achieved with PEXION®, maintain the dose and monitor – the IVETF states routine bloods should be run every 6-12 months.2
ADJUSTING THE DOSE
Clients should understand that treatment adjustment should be expected with all
idiopathic epilepsy drugs.2,3 A high percentage of cases require adjustment of the
treatment protocol to attain a successful response.
Definition of inadequate seizure control
Determined as ‘inadequate’ if seizure frequency is not reduced by at least 50%, frequency is >1 seizure per 6 weeks or there has been no reduction in seizure severity. Follow-up appointments should be used to address reduction in seizure frequency. Ask the owner to keep a record of every seizure the dog experiences to monitor duration, frequency and severity.
Follow-up
appointment
If seizure control is adequate then continue the current dose.
If seizure control is inadequate a follow-up appointment should be scheduled for a week’s time or sooner if concerned.
Consider increasing dose by:
Second follow-up appointment
If seizure control is adequate then continue the current dose.
If seizure control is inadequate a follow-up appointment should be scheduled for a week’s time or sooner if concerned.
Consider increasing dose by:
Third follow-up appointment
If seizure control is adequate then continue the current dose.
If seizure control is inadequate a follow-up appointment should be scheduled for a week’s time or sooner if concerned.
Consider addition of another medication.
PUT PEXION® ON YOUR SHELF
Make PEXION® your choice for rapid seizure control and long-term quality of life in newly diagnosed idiopathic epilepsy patients.
To have PEXION® ready for the next patient who needs it, email the person in your practice responsible for ordering from your wholesaler.
ASK OUR EXPERTS
Have any questions? Our Pet Technical Services Team are here to help.
Or call us:
UK: 01344 746957 IE: 01 291 3985